Resveratrol's 1% Problem: First-Pass Metabolism and the Under-the-Tongue Fix
The number that should bother you In 2004, a pharmacologist named Thomas Walle gave six volunteers a 25-milligram dose of radiolabeled resveratrol — the...
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Notes on the format, the labels and what we have and have not measured. Short, and only when there is something to say.
Showing posts tagged Pillar 3. Show everything
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Glutathione Supplements: What the Research Does and Doesn't Support
What Glutathione Actually Does (And Why Everyone's Suddenly Talking About It) Glutathione is a tripeptide — three amino acids (glutamate, cysteine, and glycine) bonded...
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Saffron and Emotional Eating: What the Clinical Trials Actually Show
The Pattern Most People Don't Recognize You're not hungry. You know you're not hungry. You ate dinner two hours ago, and it was a...
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Bifidobacterium Lactis: The Probiotic Strain Behind the Strip (2026)
What Bifidobacterium lactis is, why probiotic effects are strain-specific, how to read a CFU count honestly, and where a sublingual strip fits versus a...
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Curcumin Is Hard to Work With: What the Research Honestly Shows (2026)
Plain curcumin has roughly 1% oral bioavailability. Where the other 99% goes, why piperine and phytosome formulations help, and how delivery format changes what...
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Amla (Phyllanthus emblica): The Ayurvedic Wellness Berry, Honestly Reviewed (2026)
Amla (Phyllanthus emblica / Indian gooseberry) is a revered Ayurvedic rasayana rich in vitamin C and polyphenols. Here's what tradition and early research support...
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Andrographis Paniculata: The King of Bitters, Honestly Reviewed (2026)
Andrographis paniculata — the "King of Bitters" — is a traditional Ayurvedic botanical whose active compound is andrographolide. Here's what the evidence supports (immune/respiratory),...
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Chromium Picolinate and the Craving Loop: What It Actually Does (2026)
Chromium is an essential trace mineral that helps insulin work efficiently — the basis for studying it against the afternoon carb-craving loop. Here's the...
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Saffron Extract and Appetite: What the Evidence Actually Shows (2026)
Saffron (Crocus sativus) has the most interesting early research on appetite and snacking behavior — not by burning anything, but by supporting satiety signaling....
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Lion's Mane β-Glucans: What the Mushroom's Actual Active Compounds Do (2026)
Lion's Mane β-glucans and its cognitively-studied compounds are two different things. Here's what each actually does, what the human research shows (with caveats), and...
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Vegan, Halal, and Allergen-Free Supplements: What Actually Counts in 2026
Most "vegan" supplements still use gelatin capsules. Most "halal" brands aren't certified. Here's what the labels actually mean, how to read a back panel...
