The journal
Notes on the format, the labels and what we have and have not measured. Short, and only when there is something to say.
Showing posts tagged bioavailability. Show everything
Medications That Steal Your Nutrients: PPIs, Metformin, Birth Control, and the Absorption Problem I run a sublingual strip company, and this is one of...
If you spend enough time reading supplement research papers, you'll eventually hit a word that sounds like it belongs in a materials science lab,...
The number that should bother you In 2004, a pharmacologist named Thomas Walle gave six volunteers a 25-milligram dose of radiolabeled resveratrol — the...
Most "sublingual vs oral" content is marketing dressed up as science. Here's the actual pharmacokinetic data.I've published a lot of articles about sublingual absorption...
Three out of four American adults take supplements — and most have no idea how little of each dose actually reaches their bloodstream. The...
What Glutathione Actually Does (And Why Everyone's Suddenly Talking About It) Glutathione is a tripeptide — three amino acids (glutamate, cysteine, and glycine) bonded...
You set an alarm. You brush your teeth. You swallow your melatonin pill, climb into bed, and then — you wait. Twenty minutes. Thirty....
If you take a proton pump inhibitor for reflux, metformin for blood sugar, or hormonal birth control, the way your body handles vitamin B12...
Six Filters Sit Between the Label and Your Blood A note before we start: an earlier version of this article got this wrong. It...
Plain curcumin has roughly 1% oral bioavailability. Where the other 99% goes, why piperine and phytosome formulations help, and how delivery format changes what...
The two B12 forms on supplement labels behave differently — one is body-ready, one is cheaper and more stable. An honest breakdown of methylcobalamin...
The liver checkpoint that quietly destroys most of some swallowed supplements before they reach your bloodstream — what first-pass metabolism is, which nutrients it...